Organoprotective properties of fixed-drug combination verapamil-SR and trandolapril
نویسندگان
چکیده
منابع مشابه
Trandolapril/verapamil combination in hypertensive diabetic patients
Cardiovascular diseases are directly affected by arterial hypertension. When associated with diabetes mellitus, the potential deleterious effects are well amplified. Both conditions play a central role in the pathogenesis of coronary artery disease, heart failure, stroke, and renal insufficiency. Prevalence of hypertension is much higher among diabetic than non-diabetic patients, and the hypert...
متن کاملManaging hypertension in diabetic patients – focus on trandolapril/verapamil combination
Hypertensive diabetes individuals are at higher risk for cardiovascular events and progression to end stage renal disease. Several well conducted clinical trials indicate that aggressive treatment of hypertension in individual with diabetes reduces these complications. Combinations of two or more antihypertensive drugs are frequently required to reach the target blood pressure and to improve th...
متن کاملCharacteristics and outcomes of revascularized patients with hypertension: an international verapamil SR-trandolapril substudy.
Our understanding of the growing population of revascularized patients with hypertension is limited. We retrospectively analyzed the International Verapamil SR-Trandolapril Study, which randomized coronary artery disease patients with hypertension to either verapamil SR- or atenolol-based treatment strategies, focusing on characteristics and outcomes of 6166 previously revascularized patients c...
متن کاملThe effect of trandolapril and its fixed-dose combination with verapamil on proteinuria in normotensive adults with type 2 diabetes.
OBJECTIVE To compare the effect of fixed-dose trandolapril-verapamil (FDTV) with that of trandolapril on proteinuria in normotensive, type 2 diabetic patients. RESEARCH DESIGN AND METHODS A total of 60 normotensive, type 2 diabetic patients with 24-h proteinuria >300 mg were randomly assigned to two groups for open-label treatment. One group received 2 mg trandolapril/180 mg verapamil FDTV on...
متن کاملBlood pressure control and improved cardiovascular outcomes in the International Verapamil SR-Trandolapril Study.
Uncontrolled blood pressure (BP) increases cardiovascular risk, independent of type of treatment. In this posthoc International Verapamil SR-Trandolapril Study analysis, we determined whether adverse outcomes are related to consistency of BP control, defined as the proportion of visits in which BP was in control. A total of 22 576 patients with hypertension and coronary artery disease were divi...
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ژورنال
عنوان ژورنال: "Arterial’naya Gipertenziya" ("Arterial Hypertension")
سال: 2007
ISSN: 2411-8524,1607-419X
DOI: 10.18705/1607-419x-2007-13-4-266-274